{"id":7527,"date":"2025-12-09T06:16:05","date_gmt":"2025-12-09T06:16:05","guid":{"rendered":"https:\/\/cardiologylibrary.com\/?post_type=product&p=7527"},"modified":"2026-01-23T14:49:35","modified_gmt":"2026-01-23T14:49:35","slug":"penn-medicine-upenn-hfpef-symposium-2025","status":"publish","type":"product","link":"https:\/\/cardiologylibrary.com\/?product=penn-medicine-upenn-hfpef-symposium-2025","title":{"rendered":"Penn Medicine UPenn HFpEF Symposium 2025"},"content":{"rendered":"

While the incidence of heart failure with reduced ejection fraction (HFrEF) has decreased, that of heart failure with preserved ejection fraction (HFpEF) continues to rise, accounting for ~50% of heart failure hospitalizations. Patients with HFpEF suffer mentally and physically, like their HFrEF counterparts, and are markedly limited in terms of their functional capacity and quality of life. Yet in contrast to HFrEF, there are few effective pharmacologic treatments for HFpEF, despite numerous clinical trials. To address this urgent need, many clinicians and researchers have focused on this important medical and societal issue. Improved strategies now exist to diagnose this condition, and multifaceted treatment options can help to alleviate some of the morbidity of the disease.<\/p>\n

This symposium will highlight diagnostic strategies and review the evidence base for pharmacologic therapies. Treatment of comorbid conditions found in HFpEF patients will also be discussed. Additional didactics highlighting the sources of exertional intolerance in HFpEF patients will be presented, with an emphasis on cardiopulmonary exercise testing. The topics chosen for this conference represent the state-of-the-art in HFpEF management, incorporating the expertise of numerous disciplines including cardiology, pulmonology, radiology, sleep medicine, and endocrinology. The meeting is intended to provide an in-depth summary of HFpEF management to practicing clinicians across numerous disciplines, including Physicians, Nurse Practitioners, and Physician Assistants.<\/p>\n

Learning Objectives<\/strong><\/div>\n
\n

After completing this activity, participants should be able to:<\/em><\/p>\n<\/div>\n

    \n
  1. Review the diagnostic criteria for HFpEF, including when to use advanced imaging or hemodynamic assessment<\/li>\n
  2. Identify HFpEF mimickers, including amyloidosis, sarcoidosis, and inherited cardiomyopathies<\/li>\n
  3. Discuss the role of non-cardiac structures (such as the arterial system and other organs) in the pathogenesis and treatment of the patient with HFpEF<\/li>\n
  4. Describe the electrophysiologic manifestations of HFpEF and their treatments<\/li>\n
  5. Discuss novel therapies that are on the horizon for HFpEF<\/li>\n
  6. Review the potential causes of exertional intolerance in HFpEF patients.<\/li>\n<\/ol>\n

    \"\ud83e\udec0\"\u00a0The\u00a0Penn Medicine UPenn HFpEF Symposium 2025<\/strong>\u00a0is best for\u00a0cardiologists, internists, and researchers<\/strong>\u00a0focused on\u00a0Heart Failure with Preserved Ejection Fraction (HFpEF)<\/strong>. It\u2019s ideal for:<\/p>\n

    \"\ud83d\udd0d\"\u00a0What You\u2019ll Learn<\/h3>\n
      \n
    • Cutting-edge insights into\u00a0HFpEF pathophysiology, diagnostics, and therapeutics<\/strong><\/li>\n
    • Updates on\u00a0clinical trials<\/strong>,\u00a0biomarkers<\/strong>, and\u00a0multidisciplinary care models<\/strong><\/li>\n
    • Expert-led discussions on\u00a0comorbidities<\/strong>,\u00a0exercise intolerance<\/strong>, and\u00a0phenotyping strategies<\/strong><\/li>\n<\/ul>\n

      \"\ud83d\uddd3\ufe0f\"\u00a0Event Details<\/h3>\n
        \n
      • Dates<\/strong>: May 9\u201310, 2025<\/li>\n
      • Time<\/strong>: 7:30 AM \u2013 12:00 PM (ET)<\/li>\n
      • Location<\/strong>: Hybrid format \u2014 attend in person at the\u00a0Arthur H. Rubenstein Auditorium<\/strong>\u00a0(Smilow Center for Translational Research, Philadelphia) or via\u00a0live-stream<\/strong><\/li>\n<\/ul>\n

        \u00a0<\/p>\n

        + Topics:<\/strong><\/p>\n

        \n
        Friday, May 9, 2025<\/strong><\/div>\n
        \n
        \n
        In-person Sign-in and Continental Breakfast<\/strong>
        \n7:30AM \u2013 8:30AM<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Virtual Audience Sign-in (Broadcast goes live at 8:30 AM)<\/strong>
        \n8:15AM \u2013 8:30AM<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        IS IT HEART FAILURE? GETTING THE DIAGNOSIS RIGHT<\/div>\n<\/div>\n
        \n
        \n
        Welcome Address<\/strong>
        \n8:30AM \u2013 8:40AM
        \nStuart B Prenner, MD
        \nPayman Zamani, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        HFpEF Epidemiology \u2013 a Growing Problem<\/strong>
        \n8:40AM \u2013 8:55AM
        \nStuart B Prenner, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Advanced Echo Techniques to Diagnose HFpEF<\/strong>
        \n8:55AM \u2013 9:10AM
        \nJulio A Chirinos, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Advanced Imaging \u2013 PET and cMRI in HFpEF<\/strong>
        \n9:10AM \u2013 9:25AM
        \nPaco E. Bravo, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Diagnosis: Risk Scores and Catheters<\/strong>
        \n9:25AM \u2013 9:45AM
        \nBarry Borlaug, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        My Approach to Evaluation of Dyspnea<\/strong>
        \n9:45AM \u2013 10:05AM
        \nKavita Sharma, MD<\/div>\n<\/div>\n<\/div>\n
        <\/div>\n
        \n
        MINI-SYMPOSIUM: EXERCISE CAPACITY IN HFPEF<\/div>\n<\/div>\n
        \n
        \n
        Exercise Physiology, as Seen Through a CPET<\/strong>
        \n10:15AM \u2013 11:00AM
        \nJason Fritz, MD
        \nPayman Zamani, MD
        \nBenjamin D Levine, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Break and Visit Exhibits<\/strong>
        \n11:00AM \u2013 11:15AM<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Debate: It\u2019s the Heart! High Pressures Limit Exercise in HFpEF<\/strong>
        \n11:15AM \u2013 11:45AM
        \nBarry Borlaug, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Debate: There is More to HFpEF Than the Wedge<\/strong>
        \n11:45AM \u2013 12:15PM
        \nBenjamin D Levine, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Rebuttal, Q&A and Questions<\/strong>
        \n12:15PM \u2013 12:30PM<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Keynote: Patients With HFpEF Need to Exercise, But How? Logistics of Designing and Implementing an Exercise Prescription<\/strong>
        \n12:30PM \u2013 1:10PM
        \nPeter H. Brubaker, PhD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Lunch<\/strong>
        \n1:10PM \u2013 2:00PM<\/div>\n<\/div>\n<\/div>\n
        <\/div>\n
        \n
        GUIDELINE-DIRECTED PHARMACOLOGY AND DEVICES FOR HFpEF<\/div>\n<\/div>\n
        \n
        \n
        HFpEF and Nutrition<\/strong>
        \n2:00PM \u2013 2:15PM
        \nSalvatore Carbone, PhD, RDN<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        SLT2i and MRAs: The Evidence and Practical Considerations<\/strong>
        \n2:15PM \u2013 2:35PM
        \nSenthil Selvaraj, MD, MS, MA<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        HFpEF Management Guidelines and Algorithms<\/strong>
        \n2:35PM \u2013 2:50PM
        \nJeremy A Mazurek, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Ask the Experts<\/strong>
        \n2:50PM \u2013 3:05PM
        \nStuart B Prenner, MD
        \nPayman Zamani, MD
        \nSenthil Selvaraj, MD, MS, MA<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Keynote: Targeting Obesity to Target HFpEF<\/strong>
        \n3:05PM \u2013 3:45PM
        \nJaved Butler, MD, MPH<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Break<\/strong>
        \n3:45PM \u2013 4:00PM<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        MINI-SESSION: CARDIAC AMYLOIDOSIS<\/div>\n<\/div>\n
        \n
        \n
        When to Suspect Cardiac Amyloidosis and Diagnostic Strategies<\/strong>
        \n4:00PM \u2013 4:15PM
        \nJanice Pieretti, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        MRI vs. PYP for TTR for TTY Amyloid<\/strong>
        \n4:15PM \u2013 4:30PM
        \nMahesh Vidula, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Update on Amyloid Therapies<\/strong>
        \n4:30PM \u2013 4:45PM
        \nDrachman Brian, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Ask the Experts<\/strong>
        \n4:45PM \u2013 5:00PM
        \nJanice Pieretti, MD
        \nDrachman Brian, MD
        \nMahesh Vidula, MD
        \nKaylee Baker, CRNP RN<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n<\/div>\n
        \n
        Saturday, May 10, 2025<\/strong><\/div>\n
        \n
        \n
        In-person Sign-in and Continental Breakfast<\/strong>
        \n7:30AM \u2013 8:00AM<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Virtual Audience Sign-in (Broadcast goes live at 8:00 AM)<\/strong>
        \n7:45AM \u2013 8:00AM<\/div>\n<\/div>\n<\/div>\n
        <\/div>\n
        \n
        MANAGEMENT OF HFPEF RELATED COMORBIDITIES AND HFPEF MIMICKERS<\/div>\n<\/div>\n
        \n
        \n
        Recap of Day 1 and Intro to Day 2<\/strong>
        \n8:00AM \u2013 8:10AM
        \nStuart B Prenner, MD
        \nPayman Zamani, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Hypertension Management<\/strong>
        \n8:10AM \u2013 8:25AM
        \nJordana Cohen, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        GLP1: Practical Considerations and Titration<\/strong>
        \n8:25AM \u2013 8:40AM
        \nAnastassia Amaro, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Not all Hypertrophy is HFpEF<\/strong>
        \n8:40AM \u2013 8:55AM
        \nAnjali T Owens, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Chronotropic Incompetence: Modulating Sinus Rhythm and Pacing<\/strong>
        \n8:55AM \u2013 9:10AM
        \nMatthew C. Hyman, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Atrial Fibrillation in HFpEF \u2013 Screening and Treatment<\/strong>
        \n9:10AM \u2013 9:25AM
        \nDavid Frankel, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Break<\/strong>
        \n9:25AM \u2013 9:45AM<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Sleep Apnea in HFpEF<\/strong>
        \n9:45AM \u2013 10:00AM
        \nJorge Mora, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Lung Disease in HFpEF<\/strong>
        \n10:00AM \u2013 10:15AM
        \nJason Fritz, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Leveraging Remote Monitoring Technology in HFpEF<\/strong>
        \n10:15AM \u2013 10:35AM
        \nMonique S Tanna, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Rheumatologic Disease in HFpEF<\/strong>
        \n10:35AM \u2013 10:50AM
        \nBrittany Weber, MD, PhD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Keynote: HFpEF at Home \u2013 What Should We Be Telling Our Patients and What Should Our Patients Be Telling Us?<\/strong>
        \n10:50AM \u2013 11:30AM
        \nBarbara Riegel, RN<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Lunch<\/strong>
        \n11:30AM \u2013 12:20PM<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Keynote: Inflammation in HFpEF<\/strong>
        \n12:20PM \u2013 1:00PM
        \nAntonio Abbate, MD, PhD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Q&A and Break<\/strong>
        \n1:00PM \u2013 1:10PM<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Future of HFpEF Management<\/strong>
        \n1:10PM \u2013 1:50PM
        \nSanjiv Shah, MD<\/div>\n
        <\/div>\n<\/div>\n<\/div>\n
        \n
        \n
        Q&A<\/strong>
        \n1:50PM \u2013 2:00PM<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

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