While the incidence of heart failure with reduced ejection fraction (HFrEF) has decreased, that of heart failure with preserved ejection fraction (HFpEF) continues to rise, accounting for ~50% of heart failure hospitalizations. Patients with HFpEF suffer mentally and physically, like their HFrEF counterparts, and are markedly limited in terms of their functional capacity and quality of life. Yet in contrast to HFrEF, there are few effective pharmacologic treatments for HFpEF, despite numerous clinical trials. To address this urgent need, many clinicians and researchers have focused on this important medical and societal issue. Improved strategies now exist to diagnose this condition, and multifaceted treatment options can help to alleviate some of the morbidity of the disease.
This symposium will highlight diagnostic strategies and review the evidence base for pharmacologic therapies. Treatment of comorbid conditions found in HFpEF patients will also be discussed. Additional didactics highlighting the sources of exertional intolerance in HFpEF patients will be presented, with an emphasis on cardiopulmonary exercise testing. The topics chosen for this conference represent the state-of-the-art in HFpEF management, incorporating the expertise of numerous disciplines including cardiology, pulmonology, radiology, sleep medicine, and endocrinology. The meeting is intended to provide an in-depth summary of HFpEF management to practicing clinicians across numerous disciplines, including Physicians, Nurse Practitioners, and Physician Assistants.
After completing this activity, participants should be able to:
- Review the diagnostic criteria for HFpEF, including when to use advanced imaging or hemodynamic assessment
- Identify HFpEF mimickers, including amyloidosis, sarcoidosis, and inherited cardiomyopathies
- Discuss the role of non-cardiac structures (such as the arterial system and other organs) in the pathogenesis and treatment of the patient with HFpEF
- Describe the electrophysiologic manifestations of HFpEF and their treatments
- Discuss novel therapies that are on the horizon for HFpEF
- Review the potential causes of exertional intolerance in HFpEF patients.
The Penn Medicine UPenn HFpEF Symposium 2025 is best for cardiologists, internists, and researchers focused on Heart Failure with Preserved Ejection Fraction (HFpEF). It’s ideal for:
What You’ll Learn
- Cutting-edge insights into HFpEF pathophysiology, diagnostics, and therapeutics
- Updates on clinical trials, biomarkers, and multidisciplinary care models
- Expert-led discussions on comorbidities, exercise intolerance, and phenotyping strategies
Event Details
- Dates: May 9–10, 2025
- Time: 7:30 AM – 12:00 PM (ET)
- Location: Hybrid format — attend in person at the Arthur H. Rubenstein Auditorium (Smilow Center for Translational Research, Philadelphia) or via live-stream
+ Topics:
7:30AM – 8:30AM
8:15AM – 8:30AM
8:30AM – 8:40AM
Stuart B Prenner, MD
Payman Zamani, MD
8:40AM – 8:55AM
Stuart B Prenner, MD
8:55AM – 9:10AM
Julio A Chirinos, MD
9:10AM – 9:25AM
Paco E. Bravo, MD
9:25AM – 9:45AM
Barry Borlaug, MD
9:45AM – 10:05AM
Kavita Sharma, MD
10:15AM – 11:00AM
Jason Fritz, MD
Payman Zamani, MD
Benjamin D Levine, MD
11:00AM – 11:15AM
11:15AM – 11:45AM
Barry Borlaug, MD
11:45AM – 12:15PM
Benjamin D Levine, MD
12:15PM – 12:30PM
12:30PM – 1:10PM
Peter H. Brubaker, PhD
1:10PM – 2:00PM
2:00PM – 2:15PM
Salvatore Carbone, PhD, RDN
2:15PM – 2:35PM
Senthil Selvaraj, MD, MS, MA
2:35PM – 2:50PM
Jeremy A Mazurek, MD
2:50PM – 3:05PM
Stuart B Prenner, MD
Payman Zamani, MD
Senthil Selvaraj, MD, MS, MA
3:05PM – 3:45PM
Javed Butler, MD, MPH
3:45PM – 4:00PM
4:00PM – 4:15PM
Janice Pieretti, MD
4:15PM – 4:30PM
Mahesh Vidula, MD
4:30PM – 4:45PM
Drachman Brian, MD
4:45PM – 5:00PM
Janice Pieretti, MD
Drachman Brian, MD
Mahesh Vidula, MD
Kaylee Baker, CRNP RN
7:30AM – 8:00AM
7:45AM – 8:00AM
8:00AM – 8:10AM
Stuart B Prenner, MD
Payman Zamani, MD
8:10AM – 8:25AM
Jordana Cohen, MD
8:25AM – 8:40AM
Anastassia Amaro, MD
8:40AM – 8:55AM
Anjali T Owens, MD
8:55AM – 9:10AM
Matthew C. Hyman, MD
9:10AM – 9:25AM
David Frankel, MD
9:25AM – 9:45AM
9:45AM – 10:00AM
Jorge Mora, MD
10:00AM – 10:15AM
Jason Fritz, MD
10:15AM – 10:35AM
Monique S Tanna, MD
10:35AM – 10:50AM
Brittany Weber, MD, PhD
10:50AM – 11:30AM
Barbara Riegel, RN
11:30AM – 12:20PM
12:20PM – 1:00PM
Antonio Abbate, MD, PhD
1:00PM – 1:10PM
1:10PM – 1:50PM
Sanjiv Shah, MD
1:50PM – 2:00PM
Reviews
There are no reviews yet.